Living timeline·Tech industry

AMD Instinct: From MI300X to Helios and the Gigawatt Deals

Updated Sep 9, 2026 · 32 dated entries · 36 sources from Investing.com, EarningsCalls.dev, AMD Investor Relations, AMD and 2 more

Edited by Ceniy Mei · How this page is made

Tech industryAI acceleratorsAMDData center GPUs

Power lines traverse a hazy, desolate landscape, illustrating AMD Instinct: From MI300X to Helios and the Gigawatt Deals
Photo by Andrey Strizhkov on Unsplash
TL;DR

AMD introduced the Instinct MI300X in June 2023 and made it available in December, then moved to an annual accelerator roadmap spanning MI325X, MI350, MI400 and later series. Cloud deployments expanded from Azure and Oracle to production inference at Microsoft and Meta, while AMD launched the MI400 series and Helios rack-scale systems in July 2026. OpenAI, Meta and Anthropic have announced commitments for up to 14 gigawatts combined of AMD GPUs, but their initial deployments are largely still ahead; AMD said MI450 production shipments were set to begin in the third quarter of 2026, with revenue stepping up in the fourth quarter and first quarter of 2027. AMD reported $6.7 billion in second-quarter 2026 Data Center revenue, which includes EPYC as well as Instinct, and the central question is how quickly the announced GPU commitments convert into operating systems, recognized revenue and supply capacity.

Key moments

12 entries that carry the story, oldest first. The full timeline follows.

  1. Jun 13, 2023AMD unveils the Instinct MI300X with 192 GB of HBM3, sampling in Q3
  2. Dec 6, 2023MI300X and MI300A launched; Microsoft Azure, Oracle and the major OEMs line up
  3. Jun 2, 2024AMD moves Instinct to an annual cadence: MI325X in Q4 2024, MI350 in 2025, MI400 in 2026
  4. Jun 12, 2025MI350 series rolling out at Oracle; Helios rack on MI400 previewed for 2026
  5. Oct 6, 2025OpenAI agrees to deploy 6 gigawatts of AMD GPUs; AMD issues a warrant for up to 160 million shares
  6. Feb 24, 2026Meta signs for up to 6 gigawatts of AMD GPUs with a custom MI450-based part and a matching warrant
  7. Jul 20, 2026Microsoft commits to ramp Helios at scale on Azure
  8. Jul 22, 2026Anthropic to deploy up to 2 gigawatts of MI450 GPUs in Helios, starting in the first half of 2027
  9. Jul 23, 2026MI400 series launched at Advancing AI 2026; Helios customers named
  10. Aug 4, 2026Data center revenue doubles to US$6.7 billion as Helios begins to ramp
  11. Sep 8, 2026AMD says MI450 production shipments begin in Q3 2026
  12. Sep 8, 2026AMD expects Data Center sales to double in 2027

In numbers

AMD data center or Instinct revenue$6.7B as of Aug 4, 2026
Data and sources (4 points)
DateAMD data center or Instinct revenueEntry
2024$5BAMD reports more than $5 billion in 2024 Instinct revenue
2025$16.6BAMD reports $16.6 billion in 2025 Data Center revenue
May 5, 2026$5.8BAMD reports $5.8 billion in first-quarter Data Center revenue
Aug 4, 2026$6.7BData center revenue doubles to US$6.7 billion as Helios begins to ramp

Every point is a number stated in a published entry, checked against that entry's verified source quote.

Timeline

202420252026Jun 2023Sep 2026TodayJun 13, 2023: AMD unveils the Instinct MI300X with 192 GB of HBM3, sampling in Q3Dec 6, 2023: MI300X and MI300A launched; Microsoft Azure, Oracle and the major OEMs line upMay 21, 2024: Azure ND MI300X V5 instances become generally availableJun 2, 2024: AMD moves Instinct to an annual cadence: MI325X in Q4 2024, MI350 in 2025, MI400 in 2026Jul 30, 2024: AMD attributes sequential revenue growth to Instinct GPU shipmentsSep 26, 2024: Fireworks AI adopts OCI bare-metal MI300X instancesOct 10, 2024: MI325X launched at Advancing AI 2024; MI350 set for the second half of 2025Feb 4, 2025: AMD reports more than $5 billion in 2024 Instinct revenueJun 12, 2025: MI350 series rolling out at Oracle; Helios rack on MI400 previewed for 2026Jun 12, 2025: Meta says MI300X is broadly deployed for Llama inferenceJun 12, 2025: Microsoft says MI300X powers production models on AzureOct 6, 2025: OpenAI agrees to deploy 6 gigawatts of AMD GPUs; AMD issues a warrant for up to 160 million sharesOct 14, 2025: Oracle plans a public 50,000-GPU MI450 superclusterNov 4, 2025: AMD reports no MI308 shipment revenue to China in Q3Nov 11, 2025: Financial Analyst Day: data center revenue to grow more than 60 percent a year; Helios from Q3 2026Jan 5, 2026: AMD introduces MI440X and previews the MI500 seriesFeb 3, 2026: AMD releases $360 million of reserved MI308 inventory chargesFeb 3, 2026: AMD reports $16.6 billion in 2025 Data Center revenueFeb 24, 2026: Meta signs for up to 6 gigawatts of AMD GPUs with a custom MI450-based part and a matching warrantMay 5, 2026: AMD reports $5.8 billion in first-quarter Data Center revenueJul 20, 2026: Microsoft commits to ramp Helios at scale on AzureJul 22, 2026: Anthropic to deploy up to 2 gigawatts of MI450 GPUs in Helios, starting in the first half of 2027Jul 22, 2026: AMD commits up to $5 billion for a future Anthropic investmentJul 22, 2026: AMD says Anthropic was already using Instinct MI355X GPUsJul 23, 2026: MI400 series launched at Advancing AI 2026; Helios customers namedJul 23, 2026: AMD launches the Instinct MI350P GPUJul 23, 2026: AMD says OpenAI expects Helios to begin operating in Q4 2026Jul 23, 2026: AMD says Meta is validating workloads on Helios racksJul 23, 2026: AMD schedules Instinct MI600-series GPUs for 2028Aug 4, 2026: Data center revenue doubles to US$6.7 billion as Helios begins to rampSep 8, 2026: AMD says MI450 production shipments begin in Q3 2026Sep 8, 2026: AMD expects Data Center sales to double in 2027Expected Oct 2026: OpenAI expects Helios operations to beginExpected Jan 2027: Anthropic's first 1-gigawatt MI450 deployment is due to begin
32 entriesbusiest year 2026 (17)Announcements and launchesFinancial and reportsLegal and regulatorykey momentcause, response or contradictionexpected next

Earlier years show only their entries' dates and titles. Click a year heading to show the details.

202617 entries
  1. FinancialKey moment

    AMD expects Data Center sales to double in 2027

    Advanced Micro Devices said it expected its Data Center business to double in 2027 to about $70 billion in sales. The company said it had undertaken supply-chain work to support doubling Data Center revenue the following year. Su added that all three anchor customers for MI450 and Helios had given forecasts above AMD's initial expectations, and that AMD was working with suppliers to support them.

    • Investing.com · Sep 8, 2026 · “The company expects its data center business to double in 2027, reaching about $70 billion in sales.”
    • EarningsCalls.dev · Sep 8, 2026 · “So right now, we actually feel really good about all the supply chain work we have done to ensure we can support the data center revenue to double next year.”

    Editor's note: The page states that AMD expects its data center business to double in 2027 to about $70 billion in sales. It also says AMD had been working with its supply chain to support doubling data center revenue next year, and identifies the conference date as September 8, 2026.

  2. ShipmentKey moment

    AMD says MI450 production shipments begin in Q3 2026

    Advanced Micro Devices said Instinct MI450 production shipments were set to begin in the third quarter of 2026. It said revenue would step up in the fourth quarter of 2026 and again in the first quarter of 2027.

    • EarningsCalls.dev · Sep 8, 2026 · “Q3 will be the -- at the very beginning of our production shipment we expect revenue in Q3, but Q4, we'll see a very significant step up and then another step up in Q1 2027 and ramp through 2027.”
    • Investing.com · Sep 8, 2026 · “The AI GPU business continues to ramp, with MI450 set to begin production shipments in Q3 2026.”

    Editor's note: The transcript states that the MI450/Helios ramp would begin with production shipments and revenue in Q3 2026, followed by a very significant Q4 increase and another increase in Q1 2027. The page is dated 2026-09-08, matching the node date.

  3. FinancialKey moment

    Data center revenue doubles to US$6.7 billion as Helios begins to ramp

    Second-quarter 2026 results showed revenue of US$11.5 billion and data center segment revenue of US$6.7 billion, up 107 percent from a year earlier on demand for EPYC CPUs and Instinct GPUs. Lisa Su said Instinct deployments were scaling and Helios was beginning to ramp.

    • AMD Investor Relations · Aug 4, 2026 · Data Center segment revenue was $6.7 billion, up 107% year-over-year, driven by strong demand for AMD EPYC™ processors and AMD Instinct™ GPUs.
  4. Announcement

    AMD schedules Instinct MI600-series GPUs for 2028

    AMD said Instinct MI600-series GPUs were coming in 2028. The statement extended AMD's disclosed accelerator roadmap beyond the MI500 series planned for 2027.

    • AMD · Jul 23, 2026 · AMD Instinct MI600 Series GPUs are coming in 2028.

    Editor's note: The page states that AMD Instinct MI600 Series GPUs are coming in 2028 and identifies MI500 Series GPUs as coming in 2027. It is dated July 23, 2026, matching the node date.

  5. Announcement

    AMD says Meta is validating workloads on Helios racks

    AMD said Meta had begun testing and validating workloads on AMD Helios racks. AMD also said Meta was validating sixth-generation EPYC CPU platforms in its labs.

    • AMD · Jul 23, 2026 · Meta is now validating 6th Gen EPYC CPU platforms in its labs and has begun testing and validating workloads on AMD Helios racks as they prepare to deploy at scale.

    Editor's note: The page states that Meta is validating 6th Gen EPYC CPU platforms in its labs and has begun testing and validating workloads on AMD Helios racks. It is dated July 23, 2026.

  6. Announcement

    AMD says OpenAI expects Helios to begin operating in Q4 2026

    AMD said OpenAI expected to bring Helios online beginning in the fourth quarter of 2026. AMD said deployments were expected to accelerate throughout 2027.

    • AMD · Jul 23, 2026 · OpenAI expects to bring Helios online beginning in the fourth quarter of 2026, with deployments accelerating throughout 2027.

    Editor's note: The AMD press release is dated July 23, 2026 and states that OpenAI expects to bring Helios online beginning in the fourth quarter of 2026, with deployments accelerating throughout 2027.

  7. Launch

    AMD launches the Instinct MI350P GPU

    AMD launched the Instinct MI350P GPU at Advancing AI 2026. AMD said the GPU brought AI acceleration to existing infrastructure.

    • AMD · Jul 23, 2026 · AMD also launched the Instinct MI350P GPU, bringing seamless AI acceleration to existing infrastructure with leadership token economics.
    • AMD · Aug 4, 2026 · Launched the AMD Instinct MI350P GPU, designed to bring seamless AI acceleration to existing infrastructure with leadership token economics.

    Editor's note: The press release states that AMD launched the Instinct MI350P GPU at Advancing AI 2026 and includes the quoted sentence. It is dated July 23, 2026, matching the node date.

  8. LaunchKey moment

    MI400 series launched at Advancing AI 2026; Helios customers named

    AMD launched the Instinct MI400 series, with the MI455X in Helios racks for frontier AI and the MI430X for sovereign AI and HPC, and named OpenAI, Anthropic, Meta, Microsoft, Oracle, HUMAIN, Tensorwave, Vultr and Cirrascale among the organisations choosing Helios.

    • AMD Investor Relations · Jul 23, 2026 · Leading AI labs and cloud providers are choosing AMD Helios for its open, full-stack performance.
  9. Announcement

    AMD says Anthropic was already using Instinct MI355X GPUs

    AMD said Anthropic was using AMD Instinct MI355X GPUs before its planned MI450-series deployment. AMD described the planned deployment as building on that existing use.

    • AMD · Jul 22, 2026 · This deployment builds on Anthropic’s existing use of AMD Instinct MI355X GPUs.

    Editor's note: The page states that the MI450-series deployment “builds on Anthropic’s existing use of AMD Instinct MI355X GPUs.” It is dated July 22, 2026.

  10. Financial

    AMD commits up to $5 billion for a future Anthropic investment

    AMD committed to make a strategic equity investment of up to $5 billion in Anthropic in the future. The commitment was disclosed in AMD's Anthropic partnership announcement.

    • AMD · Jul 22, 2026 · AMD has committed to make a strategic equity investment of up to $5 billion in Anthropic in the future.

    Editor's note: The AMD press release states that AMD committed to make a strategic equity investment of up to $5 billion in Anthropic in the future. It is dated July 22, 2026, matching the node date.

  11. AnnouncementKey moment

    Anthropic to deploy up to 2 gigawatts of MI450 GPUs in Helios, starting in the first half of 2027

    AMD and Anthropic announced a partnership to deploy up to 2 gigawatts of Instinct MI450 series GPUs in AMD Helios rack-scale systems, with the first gigawatt beginning in the first half of 2027.

    • AMD Investor Relations · Jul 22, 2026 · with deployment of the first gigawatt beginning in the first half of 2027
  12. AnnouncementKey moment

    Microsoft commits to ramp Helios at scale on Azure

    AMD said Microsoft would ramp AMD Helios at scale on Azure. The deployment was intended to power frontier-model inference for Microsoft, its AI customers and Azure AI services.

    • AMD · Jul 20, 2026 · Microsoft to ramp AMD Helios™ at scale on Azure to power frontier model inference for Microsoft, its AI customers and Azure AI services.

    Editor's note: The AMD press release states that Microsoft will ramp AMD Helios at scale on Azure for frontier-model inference for Microsoft, its AI customers, and Azure AI services. It is dated and released July 20, 2026.

  13. Financial

    AMD reports $5.8 billion in first-quarter Data Center revenue

    AMD reported $5.8 billion in first-quarter 2026 Data Center segment revenue, up 57% year over year. AMD attributed the result to EPYC processor demand and the continued ramp of Instinct GPU shipments.

    • AMD · May 5, 2026 · Data Center segment revenue was $5.8 billion, up 57% year-over-year, driven by strong demand for AMD EPYC™ processors and the continued ramp of AMD Instinct™ GPU shipments.

    Editor's note: The page states that AMD reported first-quarter 2026 Data Center segment revenue of $5.8 billion, up 57% year over year, driven by EPYC processor demand and the ramp of Instinct GPU shipments. It is dated May 05, 2026.

  14. AnnouncementKey moment

    Meta signs for up to 6 gigawatts of AMD GPUs with a custom MI450-based part and a matching warrant

    AMD and Meta agreed a multi-year, multi-generation partnership to deploy up to 6 gigawatts of Instinct GPUs. Shipments for the first gigawatt were expected to begin in the second half of 2026 using a custom GPU based on the MI450 architecture, and AMD issued Meta a performance-based warrant for up to 160 million shares.

    • AMD Investor Relations · Feb 24, 2026 · AMD has issued Meta a performance-based warrant for up to 160 million shares of AMD common stock, structured to vest as specific milestones associated with Instinct GPU shipments are achieved.
    • AMD Form 8-K · Feb 24, 2026 · On February 23, 2026, in connection with a strategic arrangement between Advanced Micro Devices, Inc. (“AMD”) and Meta Platforms, Inc. (“Meta”) governing the purchase of AMD Instinct™ GPU products by Meta, AMD issued to Meta a performance-based warrant (the “Warrant”) to purchase up to an aggregate of 160 million shares of common stock of AMD (the “Warrant Shares”) at an exercise price of $0.01 per share.
  15. Financial

    AMD reports $16.6 billion in 2025 Data Center revenue

    AMD reported full-year 2025 Data Center segment revenue of $16.6 billion. It said the result reflected growth in EPYC CPUs and Instinct GPUs.

    • AMD · Feb 3, 2026 · For the full year 2025, Data Center segment revenue was a record $16.6 billion, up 32% year-over-year, reflecting growth across both EPYC CPUs and AMD Instinct GPUs.

    Editor's note: The page states that full-year 2025 Data Center segment revenue was a record $16.6 billion, up 32% year over year, reflecting growth across EPYC CPUs and AMD Instinct GPUs. The press release is dated February 3, 2026.

  16. Financial

    AMD releases $360 million of reserved MI308 inventory charges

    AMD said it benefited from an approximate $360 million release of previously reserved MI308 inventory and related charges in the fourth quarter. The release concerned AMD Instinct MI308 inventory.

    • AMD · Feb 3, 2026 · In the fourth quarter, AMD benefited from an approximate $360 million release of previously reserved AMD Instinct™ MI308 inventory and related charges.

    Editor's note: The page states that AMD benefited from an approximate $360 million release of previously reserved AMD Instinct MI308 inventory and related charges in the fourth quarter. The press release is dated February 3, 2026.

  17. Announcement

    AMD introduces MI440X and previews the MI500 series

    AMD introduced the Instinct MI440X GPU for enterprise deployments. It also previewed the next-generation Instinct MI500 Series GPUs.

    • AMD · Jan 5, 2026 · AMD expanded its AI portfolio with the introduction of the AMD Instinct MI440X GPU for enterprise deployments and previewed the next-generation Instinct MI500 Series GPUs

    Editor's note: The page states that AMD introduced the Instinct MI440X GPU for enterprise deployments and previewed the next-generation MI500 Series GPUs. It is dated January 05, 2026, matching the node date.

20258 entries
  1. Financial

    Financial Analyst Day: data center revenue to grow more than 60 percent a year; Helios from Q3 2026

    AMD set long-term targets of more than 35 percent annual revenue growth, a non-GAAP operating margin above 35 percent and earnings per share above US$20, with data center revenue growing more than 60 percent a year. It said Helios systems with MI450 GPUs would begin delivering in the third quarter of 2026.

    • AMD Investor Relations · Nov 11, 2025 · AMD expects to deliver a greater than 60% revenue CAGR for its data center business.
  2. Regulatory

    AMD reports no MI308 shipment revenue to China in Q3

    AMD said its third-quarter results included no revenue from MI308 GPU shipments to China. The disclosure concerned AMD Instinct MI308 products.

    • AMD · Nov 4, 2025 · Our third quarter results did not include any revenue from shipments of AMD Instinct™ MI308 GPU products to China.

    Editor's note: The page states that third-quarter 2025 results did not include revenue from shipments of AMD Instinct MI308 GPU products to China. It is dated November 04, 2025.

  3. Announcement

    Oracle plans a public 50,000-GPU MI450 supercluster

    Oracle plans a public 50,000-GPU MI450 supercluster
    Image: AMD, press image · source · editorial use

    AMD said Oracle would be the first hyperscaler to offer a publicly available AI supercluster powered by 50,000 MI450 Series GPUs. The offering was scheduled to begin in the third quarter of 2026.

    • AMD Newsroom · Oct 14, 2025 · Beginning in the third quarter of 2026, Oracle will be the first hyperscaler to offer a publicly available AI supercluster powered by 50,000 AMD Instinct MI450 Series GPUs.

    Editor's note: Quote confirmed verbatim on the AMD newsroom page dated October 14, 2025 (editor re-check); the automated pass misread the rendered text.

  4. AnnouncementKey moment

    OpenAI agrees to deploy 6 gigawatts of AMD GPUs; AMD issues a warrant for up to 160 million shares

    AMD and OpenAI announced a multi-year agreement under which OpenAI will deploy 6 gigawatts of AMD Instinct GPUs across generations, starting with 1 gigawatt of MI450 GPUs in the second half of 2026. AMD issued OpenAI a warrant for up to 160 million shares at US$0.01 that vests with deployment milestones and AMD share-price targets.

    • AMD Investor Relations · Oct 6, 2025 · The first 1 gigawatt deployment of AMD Instinct MI450 GPUs is set to begin in the second half of 2026.
  5. Announcement

    Microsoft says MI300X powers production models on Azure

    AMD reported that Microsoft said Instinct MI300X was powering proprietary and open-source models in production on Azure. The statement concerned Azure production workloads.

    • AMD · Jun 12, 2025 · Microsoft announced Instinct MI300X is now powering both proprietary and open-source models in production on Azure.

    Editor's note: The page states that Microsoft announced Instinct MI300X is powering both proprietary and open-source models in production on Azure. The press release is dated June 12, 2025.

  6. Announcement

    Meta says MI300X is broadly deployed for Llama inference

    AMD reported that Meta detailed broad MI300X deployment for Llama 3 and Llama 4 inference. The statement concerned AMD Instinct MI300X deployments.

    • AMD · Jun 12, 2025 · Meta detailed how Instinct MI300X is broadly deployed for Llama 3 and Llama 4 inference.

    Editor's note: The press release states that “Meta detailed how Instinct MI300X is broadly deployed for Llama 3 and Llama 4 inference.” It is dated June 12, 2025.

  7. LaunchKey moment

    MI350 series rolling out at Oracle; Helios rack on MI400 previewed for 2026

    At Advancing AI 2025 AMD said MI350 series accelerators were already deploying at Oracle Cloud Infrastructure with broad availability in the second half of 2025, and previewed Helios, a rack-scale system built on the coming MI400 series GPUs, Zen 6 EPYC "Venice" CPUs and Pensando "Vulcano" NICs.

    • AMD Investor Relations · Jun 12, 2025 · AMD demonstrated end-to-end, open-standards rack-scale AI infrastructure—already rolling out with AMD Instinct MI350 Series accelerators, 5th Gen AMD EPYC™ processors and AMD Pensando™ Pollara NICs in hyperscaler deployments such as Oracle Cloud Infrastructure (OCI) and set for broad availability in 2H 2025.
  8. Financial

    AMD reports more than $5 billion in 2024 Instinct revenue

    AMD said it delivered more than $5 billion of AMD Instinct accelerator revenue during 2024. It said Data Center annual revenue nearly doubled as EPYC adoption accelerated.

    • AMD · Feb 4, 2025 · Data Center segment annual revenue nearly doubled as EPYC processor adoption accelerated and we delivered more than $5 billion of AMD Instinct accelerator revenue.

    Editor's note: The page states that AMD delivered more than $5 billion of AMD Instinct accelerator revenue during 2024 and that Data Center segment annual revenue nearly doubled as EPYC adoption accelerated. It is dated February 4, 2025.

  1. Nov 11, 2025Financial Analyst Day: data center revenue to grow more than 60 percent a year; Helios from Q3 2026
  2. Nov 4, 2025AMD reports no MI308 shipment revenue to China in Q3
  3. Oct 14, 2025Oracle plans a public 50,000-GPU MI450 supercluster
  4. Oct 6, 2025OpenAI agrees to deploy 6 gigawatts of AMD GPUs; AMD issues a warrant for up to 160 million shares
  5. Jun 12, 2025Microsoft says MI300X powers production models on Azure
  6. Jun 12, 2025Meta says MI300X is broadly deployed for Llama inference
  7. Jun 12, 2025MI350 series rolling out at Oracle; Helios rack on MI400 previewed for 2026
  8. Feb 4, 2025AMD reports more than $5 billion in 2024 Instinct revenue
20245 entries
  1. Launch

    MI325X launched at Advancing AI 2024; MI350 set for the second half of 2025

    AMD launched the Instinct MI325X, shared details of the MI350 series expected in the second half of 2025, and said the MI400 series based on CDNA Next remained planned for 2026.

    • AMD Investor Relations · Oct 10, 2024 · AMD also shared new details on next-gen AMD Instinct MI350 series accelerators expected to launch in the second half of 2025, extending AMD Instinct leadership memory capacity and generative AI performance.
  2. Launch

    Fireworks AI adopts OCI bare-metal MI300X instances

    AMD said OCI bare-metal instances using MI300X accelerators had been adopted by Fireworks AI. The instances were part of Oracle Cloud Infrastructure's MI300X offering.

    • AMD · Sep 26, 2024 · These OCI bare metal instances have already been adopted by companies including Fireworks AI.

    Editor's note: The AMD press release states that OCI chose MI300X accelerators for its BM.GPU.MI300X.8 bare-metal instance and that these instances had already been adopted by companies including Fireworks AI. It is dated September 26, 2024.

  3. Financial

    AMD attributes sequential revenue growth to Instinct GPU shipments

    AMD reported that revenue increased 21% sequentially. It attributed the increase primarily to the ramp of AMD Instinct GPU shipments.

    • AMD · Jul 30, 2024 · Revenue increased 21% sequentially primarily driven by the strong ramp of AMD Instinct GPU shipments.

    Editor's note: The page is readable and states that Data Center segment revenue increased 21% sequentially, primarily driven by the strong ramp of AMD Instinct GPU shipments. It is dated July 30, 2024.

  4. AnnouncementKey moment

    AMD moves Instinct to an annual cadence: MI325X in Q4 2024, MI350 in 2025, MI400 in 2026

    At Computex in Taipei AMD laid out a yearly roadmap for its AI accelerators: the MI325X with 288 GB of HBM3E in the fourth quarter of 2024, the CDNA 4-based MI350 series in 2025, and the MI400 series on a CDNA "Next" architecture in 2026.

    • AMD Investor Relations · Jun 2, 2024 · New AMD Instinct MI325X accelerator expected to be available in Q4 2024 with up to 288GB of HBM3E memory
  5. Launch

    Azure ND MI300X V5 instances become generally available

    AMD said Azure ND MI300X V5 instances were generally available. Hugging Face was identified as the first customer.

    • AMD · May 21, 2024 · The new Azure ND MI300X V5 instances are now generally available, with Hugging Face as the first customer

    Editor's note: The AMD press release states that the new Azure ND MI300X V5 instances are generally available and names Hugging Face as the first customer. It is dated May 21, 2024.

  1. Oct 10, 2024MI325X launched at Advancing AI 2024; MI350 set for the second half of 2025
  2. Sep 26, 2024Fireworks AI adopts OCI bare-metal MI300X instances
  3. Jul 30, 2024AMD attributes sequential revenue growth to Instinct GPU shipments
  4. Jun 2, 2024AMD moves Instinct to an annual cadence: MI325X in Q4 2024, MI350 in 2025, MI400 in 2026
  5. May 21, 2024Azure ND MI300X V5 instances become generally available
20232 entries
  1. LaunchKey moment

    MI300X and MI300A launched; Microsoft Azure, Oracle and the major OEMs line up

    At Advancing AI 2023 AMD announced availability of the MI300X accelerator and the MI300A APU. Microsoft announced Azure virtual machines built on MI300X, Oracle Cloud planned MI300X offerings, and Dell, HPE, Lenovo and Supermicro showed systems using the parts.

    • AMD Investor Relations · Dec 6, 2023 · Today, AMD announced the availability of the AMD Instinct™ MI300X accelerators – with industry leading memory bandwidth for generative AI and leadership performance for large language model (LLM) training and inferencing – as well as the AMD Instinct™ MI300A accelerated processing unit (APU).
  2. AnnouncementKey moment

    AMD unveils the Instinct MI300X with 192 GB of HBM3, sampling in Q3

    At its Data Center and AI Technology Premiere AMD introduced the MI300X, a GPU-only version of the MI300 family built on the CDNA 3 architecture with up to 192 GB of HBM3 memory, aimed at large language model training and inference, and said it would sample to key customers from the third quarter.

  1. Dec 6, 2023MI300X and MI300A launched; Microsoft Azure, Oracle and the major OEMs line up
  2. Jun 13, 2023AMD unveils the Instinct MI300X with 192 GB of HBM3, sampling in Q3

Cause and effect

  1. OpenAI agrees to deploy 6 gigawatts of AMD GPUs; AMD issues a warrant for up to 160 million sharesled to →Financial Analyst Day: data center revenue to grow more than 60 percent a year; Helios from Q3 2026The OpenAI agreement underpinned the 60 percent data center growth target set five weeks later.

Where sources disagree or fall silent

  • The OpenAI, Meta and Anthropic agreements describe maximum or expected deployment volumes; the entries do not show how much capacity has been delivered, is operating, or has generated revenue.
  • AMD said MI450 production shipments were set to begin in the third quarter of 2026, while OpenAI expects Helios operations to start in the fourth quarter; the actual start and scale of either deployment are not yet disclosed.
  • Reported Data Center revenue combines EPYC processor and Instinct GPU sales, so the entries do not isolate the revenue contribution from Instinct accelerators or Helios.
  • The timeline does not explain in detail how the MI450 product name relates to the MI400-series launch and its MI455X Helios GPU.
  • Oracle planned to begin offering a public 50,000-GPU MI450 supercluster in the third quarter of 2026, but these entries do not confirm that the offering has started.
  • The entries do not disclose whether any OpenAI or Meta warrant tranches have vested, nor the eventual amount of AMD share dilution from the warrants.

What to watch next

Who is involved

  • AMDcompany

    Designer and supplier of Instinct accelerators and Helios systems, pursuing large AI infrastructure deployments.

  • Lisa Superson

    AMD chief executive who said Instinct deployments were scaling and Helios was beginning to ramp in the second quarter of 2026.

  • Heliosproduct

    AMD's rack-scale AI system combining Instinct GPUs, Zen 6 EPYC CPUs and Pensando networking; it is the platform for the planned large deployments.

  • Instinct MI450product

    The GPU inside Helios and the gigawatt deals.

  • AMD EPYCproduct

    AMD server CPUs used in Helios and a material contributor, alongside Instinct GPUs, to reported Data Center revenue growth.

  • Microsoftcompany

    Made MI300X Azure instances available, reported production model use on Azure, and committed to ramp Helios at scale.

  • AMD Heliosproduct

    AMD's rack-scale AI system combining Instinct GPUs, EPYC CPUs and Pensando networking; it is the planned deployment platform for the large MI450 agreements.

  • AMD Instinctproduct

    AMD's data center AI accelerator line, progressing from MI300X through the MI400 generation and planned later generations.

29 more
  • AMD Instinct MI300Xproduct

    GPU used in Azure and OCI deployments.

  • Oraclecompany

    Early cloud deployer of MI350 systems and planned provider of a public 50,000-GPU MI450 supercluster.

  • AMD Instinct MI350 seriesproduct

    The 2025 generation, including MI355X and MI350P, deployed at Oracle and already used by Anthropic before its planned MI450 deployment.

  • Anthropiccompany

    Already uses MI355X and agreed to deploy up to 2 gigawatts of MI450 GPUs in Helios systems; AMD also committed up to $5 billion for a future strategic investment.

  • Azureproduct

    Microsoft's cloud platform, where MI300X instances became generally available and production models have run on MI300X.

  • Metacompany

    Broadly deployed MI300X for Llama inference, agreed to deploy up to 6 gigawatts of AMD GPUs, and is validating Helios racks.

  • OpenAIcompany

    Agreed to deploy 6 gigawatts of AMD Instinct GPUs, beginning with 1 gigawatt of MI450-class GPUs, and received a performance-based warrant for up to 160 million AMD shares.

  • GPU supplier that discussed production shipments, revenue expectations, product roadmap timing, and customer forecasts.

  • AMD Instinct MI308product

    A China-related accelerator product for which AMD reported no third-quarter 2025 shipment revenue and later released reserved inventory charges.

  • AMD Instinct MI400 series and MI450 GPUsproduct

    The MI400 generation launched in July 2026; MI455X is the Helios frontier-AI GPU, while the OpenAI, Meta and Anthropic agreements refer to MI450-series deployments or architecture.

  • AMD Instinct MI500product

    Next-generation GPU series previewed by AMD.

  • AMD ROCmproduct

    AMD software platform referenced in planned MI455X and Helios configurations.

  • Instinct MI300Xproduct

    2023 generation, 192 GB HBM3.

  • AMD Instinct MI350Pproduct

    GPU launched for existing infrastructure.

  • AMD Instinct MI355Xproduct

    GPU that AMD said Anthropic was already using.

  • AMD Instinct MI440Xproduct

    An accelerator introduced for enterprise deployments in January 2026.

  • AMD Instinct MI450product

    The GPU generation named in the OpenAI, Meta and Anthropic commitments; AMD said production shipments were set to begin in the third quarter of 2026.

  • AMD Instinct MI600product

    Future GPU series AMD said was coming in 2028.

  • AMD Pensandoproduct

    AMD networking product line named in the Helios 600 roadmap.

  • Chinaother

    Market affected by U.S. restrictions on the MI308, with no MI308 shipment revenue reported by AMD in the third quarter of 2025.

  • Fireworks AIcompany

    Adopted OCI bare-metal instances using MI300X accelerators.

  • Identified as the first customer for Azure ND MI300X V5 instances.

  • Llama 3product

    Model used for inference on broadly deployed MI300X systems.

  • Llama 4product

    Model used for inference on broadly deployed MI300X systems.

  • Received AMD's performance-based warrant and tested workloads on Helios racks.

  • OCIproduct

    Oracle Cloud Infrastructure platform offering MI300X instances.

  • Oracle's cloud platform, which offered MI300X bare-metal instances and began deploying MI350 accelerators.

  • Tritonproduct

    OpenAI framework referenced in AMD's Helios workload-optimization statement.

  • TSMCcompany

    Supply-chain company named in AMD's Data Center growth discussion.

Changelog

Changes to this timeline. All timelines' changes.

  • Chart data refreshed: 4 point(s) across 1 metric(s).
  • Summary, key players and catalysts refreshed.
  • Added 2 node(s): 2026-09-08 AMD says MI450 production shipments begin in Q3 2026; 2026-09-08 AMD expects Data Center sales to double in 2027.
  • Research run found 5 candidate node(s).
  • Chart data refreshed: 4 point(s) across 1 metric(s).
  • Summary, key players and catalysts refreshed.
  • Summary, key players and catalysts refreshed.
  • Added 19 node(s): 2024-05-21 Azure ND MI300X V5 instances become generally available; 2024-07-30 AMD attributes sequential revenue growth to Instinct GPU shipments; 2024-09-26 Fireworks AI adopts OCI bare-metal MI300X instances; 2025-02-04 AMD reports more than $5 billion in 2024 Instinct revenue and 15 more.
  • Research run found 10 candidate node(s).
  • Research run found 13 candidate node(s).
  • Seeded 11 hand-verified node(s) from amd-instinct-ai-gpus.yaml.

A research pass records each dated fact with the page it came from and a verbatim quote. A second, independent pass re-opens every cited page and rejects entries it cannot confirm. The editor reviews what remains before it is published, and every change is listed above. Full method.